Structure of PDB 6tb3 Chain BW

Receptor sequence
>6tb3BW (length=112) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SQRKLQQDIDKLLKKVKEGIEDFDDIYEKFQSTDPSNSSHREKLESDLKR
EIKKLQKHRDQIKTWLSKEDVKDKQSVLMTNRRLIENGMERFKSVEKLMK
TKQFSKEALTNP
3D structure
PDB6tb3 The Ccr4-Not complex monitors the translating ribosome for codon optimality.
ChainBW
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna BW S40 K44 F105 S39 K43 F104
BS02 rna BW Q57 R60 K69 E87 E91 K101 K103 F105 S106 K107 Q56 R59 K68 E86 E90 K100 K102 F104 S105 K106
BS03 rna BW R4 Q8 K54 K55 K58 R3 Q7 K53 K54 K57
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus
GO:0030015 CCR4-NOT core complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6tb3, PDBe:6tb3, PDBj:6tb3
PDBsum6tb3
PubMed32299921
UniProtQ12514|NOT5_YEAST General negative regulator of transcription subunit 5 (Gene Name=NOT5)

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