Structure of PDB 4v7t Chain BW

Receptor sequence
>4v7tBW (length=79) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
GGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRD
HTLFAKADGKVKFEVKGPKNRKFISIEAE
3D structure
PDB4v7t Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
ChainBW
Resolution3.1942 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna BW R10 N11 G12 D14 E16 K18 R19 L20 V22 K23 R24 F25 E28 V30 L31 A32 R38 Q39 R40 F44 G53 R54 D55 F59 F68 R76 K77 R5 N6 G7 D9 E11 K13 R14 L15 V17 K18 R19 F20 E23 V25 L26 A27 R33 Q34 R35 F39 G48 R49 D50 F54 F63 R71 K72
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0043022 ribosome binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0001558 regulation of cell growth
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042256 cytosolic ribosome assembly
GO:0090070 positive regulation of ribosome biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:4v7t, PDBe:4v7t, PDBj:4v7t
PDBsum4v7t
PubMed20876128
UniProtP0A7L8|RL27_ECOLI Large ribosomal subunit protein bL27 (Gene Name=rpmA)

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