Structure of PDB 4v6b Chain BW

Receptor sequence
>4v6bBW (length=161) Species: 9606 (Homo sapiens) [Search protein sequence]
MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSH
FFRELAEEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAA
MALEKKLNQALLDLHALGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLT
NLHRLGGPEAG
3D structure
PDB4v6b Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration
ChainBW
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA BW D128 E131 D128 E131
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
Cellular Component
GO:0044754 autolysosome

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Cellular Component
External links
PDB RCSB:4v6b, PDBe:4v6b, PDBj:4v6b
PDBsum4v6b
PubMed19923220
UniProtQ6S4P3

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