Structure of PDB 4u1v Chain BW

Receptor sequence

>4u1vBW (length=76) Species: 83333 (Escherichia coli K-12)

TRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTL
FAKADGKVKFEVKGPKNRKFISIEAE

3D structure

• PDB: 4u1v Synergy of streptogramin antibiotics occurs independently of their effects on translation.
• Chain: BW
• Resolution: 3.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BW	R11 N12 R14 D15 S16 E17 A18 K19 R20 K24 F26 G27 E29 L32 A33 G34 S35 I36 R39 R41 G42 T43 K44 H46 G54 R55 D56 H57 T58 F60 F69 R77	R2 N3 R5 D6 S7 E8 A9 K10 R11 K15 F17 G18 E20 L23 A24 G25 S26 I27 R30 R32 G33 T34 K35 H37 G45 R46 D47 H48 T49 F51 F60 R68
BS02	rna	BW	G73 P74 N76	G64 P65 N67

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome

External links

• PDB: RCSB:4u1v, PDBe:4u1v, PDBj:4u1v
• PDBsum: 4u1v
• PubMed: 24957822
• UniProt: P0A7L8|RL27_ECOLI Large ribosomal subunit protein bL27 (Gene Name=rpmA)