Structure of PDB 4v9o Chain BV

Receptor sequence

>4v9oBV (length=690) Species: 83333 (Escherichia coli K-12)

ARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNAATMDWMEQEQERG
ITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAV
MVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKT
RLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPAD
MVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNE
IILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERH
ASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERF
GRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILERME
FPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAG
MGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQSG
GRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQ
LKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKP
VLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPL
SEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIE

3D structure

• PDB: 4v9o Control of ribosomal subunit rotation by elongation factor G.
• Chain: BV
• Resolution: 2.9 Å

Enzymatic activity

• Enzyme Commision number: 3.6.5.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BV	H18 H92 R146 E463 L464 K507 E625 T628 G629 G633 R637 L642 K643 G644 Q645 R671 S672 K675	H17 H82 R136 E453 L454 K497 E615 T618 G619 G623 R627 L632 K633 G634 Q635 R661 S662 K665
BS02	rna	BV	P328 F329 V330 G331 R359 R362 S509	P318 F319 V320 G321 R349 R352 S499
BS03	MG	BV	T24 T62	T23 T52

Gene Ontology

Molecular Function

• GO:0003746 translation elongation factor activity
• GO:0003924 GTPase activity
• GO:0005525 GTP binding
• GO:0016787 hydrolase activity
• GO:0097216 guanosine tetraphosphate binding

Biological Process

• GO:0006412 translation
• GO:0006414 translational elongation
• GO:0032790 ribosome disassembly

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:4v9o, PDBe:4v9o, PDBj:4v9o
• PDBsum: 4v9o
• PubMed: 23812721
• UniProt: P0A6M8|EFG_ECOLI Elongation factor G (Gene Name=fusA)