Structure of PDB 5mc6 Chain BT

Receptor sequence
>5mc6BT (length=154) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
EEHTFETADAGSSATYPMQCSALRKNGFVVIKSRPCKIVDMSTSKTGKHG
HAKVHLVAIDIFTGKKLEDLSPSTHNMEVPVVKRNEYQLLDIDDGFLSLM
NMDGDTKDDVKAPEGELGDSLQTAFDEGKDLMVTIISAMGEEAAISFKEA
ARTD
3D structure
PDB5mc6 The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex.
ChainBT
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna BT R27 X51 R87 K151 R24 X48 R84 K148
BS02 rna BT K48 T49 G50 X51 H52 G53 H54 K56 K69 E71 L73 P75 H78 K45 T46 G47 X48 H49 G50 H51 K53 K66 E68 L70 P72 H75
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0003746 translation elongation factor activity
GO:0005515 protein binding
GO:0043022 ribosome binding
Biological Process
GO:0002182 cytoplasmic translational elongation
GO:0002184 cytoplasmic translational termination
GO:0006412 translation
GO:0006413 translational initiation
GO:0006414 translational elongation
GO:0006452 translational frameshifting
GO:0045901 positive regulation of translational elongation
GO:0045905 positive regulation of translational termination
GO:0045948 positive regulation of translational initiation
GO:0072344 rescue of stalled ribosome
GO:0097622 cytoplasmic translational elongation through polyproline stretches
GO:0140708 CAT tailing
GO:1903272 positive regulation of cytoplasmic translational elongation through polyproline stretches
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0048471 perinuclear region of cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5mc6, PDBe:5mc6, PDBj:5mc6
PDBsum5mc6
PubMed27980209
UniProtP23301|IF5A1_YEAST Eukaryotic translation initiation factor 5A-1 (Gene Name=HYP2)

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