Structure of PDB 4v6u Chain BS

Receptor sequence

>4v6uBS (length=150) Species: 186497 (Pyrococcus furiosus DSM 3638)

GYSFQNFDPKRMARASARDLRISPKLAVEVCRELRGMMLNDALRYLDDVI
ALKRPVPLKRYNDSQGHKPGKGFGPGRYPVKVAKAIKKVLLNVKNNAVQK
GLDPDKLKIIHIAAHKGPVLRGWYPRAFGRATPFNEQTTHIEVVVEEIRR

3D structure

• PDB: 4v6u Promiscuous behaviour of archaeal ribosomal proteins: Implications for eukaryotic ribosome evolution.
• Chain: BS
• Resolution: 6.6 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BS	Y7 S8 F9 S21 R23 R26 S28 K30 R37 R40 K64 R65 Y66 N67 D68 S69 Q70 H72 K73 P74 K76 F78 R82 Y83 K86 K93 N97 N100 Q104 H116 A118 A119 H120 K121 G122 P123 R126 Y129 P130 R131 A132 F133 R135 T137 P138 F139 N140 E141 R155	Y2 S3 F4 S16 R18 R21 S23 K25 R32 R35 K59 R60 Y61 N62 D63 S64 Q65 H67 K68 P69 K71 F73 R77 Y78 K81 K88 N92 N95 Q99 H111 A113 A114 H115 K116 G117 P118 R121 Y124 P125 R126 A127 F128 R130 T132 P133 F134 N135 E136 R150

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v6u, PDBe:4v6u, PDBj:4v6u
• PDBsum: 4v6u
• PubMed: 23222135
• UniProt: Q8U003|RL22_PYRFU Large ribosomal subunit protein uL22 (Gene Name=rpl22)