Structure of PDB 4v6a Chain BQ

Receptor sequence

>4v6aBQ (length=138) Species: 300852 (Thermus thermophilus HB8)

MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAA
RVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPG
RVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYD

3D structure

• PDB: 4v6a Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome.
• Chain: BQ
• Resolution: 3.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BQ	P4 R5 R6 K8 Y9 K11 Q13 R14 R16 K22 G23 G24 F29 A40 W41 Q46 A49 R56 F69 Y74 T75 K76 K77 E80 R82 M83 G84 K85 G86 K87 R101 R119 H123 K124 P126 K128	P4 R5 R6 K8 Y9 K11 Q13 R14 R16 K22 G23 G24 F29 A40 W41 Q46 A49 R56 F69 Y74 T75 K76 K77 E80 R82 M83 G84 K85 G86 K87 R101 R119 H123 K124 P126 K128
BS02	rna	BQ	L17 K18 G19	L17 K18 G19

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v6a, PDBe:4v6a, PDBj:4v6a
• PDBsum: 4v6a
• PubMed: 19696344
• UniProt: P60489|RL16_THET8 Large ribosomal subunit protein uL16 (Gene Name=rplP)