Structure of PDB 8ove Chain BP

Receptor sequence
>8oveBP (length=154) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
VKANYIRAGRLVRILRGPRQNRVGVIVDIVDANRVLVENPCEQKMWRHVQ
NLKNVEPLKFCVSISRNCSTKALKEALESKKVLEKYAATKSAVRIAAKKA
FAESTDFERYQLRVAKRSRAYWARKIFDDNDKKNPVSWHKVALKKLLKNA
KKVD
3D structure
PDB8ove A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.
ChainBP
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna BP R17 P19 R20 K45 W47 H49 V50 N52 N55 N68 R16 P18 R19 K44 W46 H48 V49 N51 N54 N67
BS02 rna BP K146 N150 K153 K145 N149 K152
BS03 rna BP V2 K3 Y6 R114 V115 R118 Y122 R125 W139 V1 K2 Y5 R113 V114 R117 Y121 R124 W138
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ove, PDBe:8ove, PDBj:8ove
PDBsum8ove
PubMed37985661
UniProtQ383F5

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