Structure of PDB 8cq7 Chain BO

Receptor sequence

>8cq7BO (length=159) Species: 5476 (Candida albicans) [Search protein sequence]

GKSRGYRSGTRYAFQRDFKKHGAIPLSTYLKVYKVGDIVDIKANGSIQKG
MPHKYYHGKTGIVYNVTKSSVGVIINKVVGNRYIEKRVNLRVEHVKHSAC
RQEFLNRVKSNAAKKREAKANGETVYLKRQAAKPRGSRIISTEGNIPQTL
APVAYETFI

3D structure

PDB

8cq7 Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.2 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BO	G2 K3 S4 R5 G6 Y7 R8 S9 G10 R12 Y13 A14 R17 F19 H22 G23 K35 G46 S47 Q49 K50 G51 H54 K55 Y57 H58 G59 K60 T61 T68 K69 S70 S71 K78 V80 R83 K87 R88 N90 R92 A100 R102 E104 F105 R108 V109 K116 K120 Y127 L128 K129 R130	G1 K2 S3 R4 G5 Y6 R7 S8 G9 R11 Y12 A13 R16 F18 H21 G22 K34 G45 S46 Q48 K49 G50 H53 K54 Y56 H57 G58 K59 T60 T67 K68 S69 S70 K77 V79 R82 K86 R87 N89 R91 A99 R101 E103 F104 R107 V108 K115 K119 Y126 L127 K128 R129
BS02	rna	BO	P26 L27 S28	P25 L26 S27

External links

PDB	RCSB:8cq7, PDBe:8cq7, PDBj:8cq7
PDBsum	8cq7
PubMed
UniProt	A0A8H6F1C8

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