Structure of PDB 4v9c Chain BO

Receptor sequence

>4v9cBO (length=116) Species: 83333 (Escherichia coli K-12) [Search protein sequence]

DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAA
STVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHG
RVQALADAAREAGLQF

3D structure

PDB

4v9c Allosteric control of the ribosome by small-molecule antibiotics.

Chain

Resolution

3.3 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BO	R9 R10 T12 R13 A14 R16 K17 L21 S91 F92 R94 Q98 Y99 R111 F117	R8 R9 T11 R12 A13 R15 K16 L20 S90 F91 R93 Q97 Y98 R110 F116
BS02	rna	BO	K3 R15 R25 H29 T31 P32 R33 H34 Y36 Q38 G44 S45 E46 V47 E55 K56 Y64 N67 K68 Q98 H100 G101 R102	K2 R14 R24 H28 T30 P31 R32 H33 Y35 Q37 G43 S44 E45 V46 E54 K55 Y63 N66 K67 Q97 H99 G100 R101

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding
GO:0019843	rRNA binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:4v9c, PDBe:4v9c, PDBj:4v9c
PDBsum	4v9c
PubMed	22902368
UniProt	P0C018\|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)