Structure of PDB 4v6o Chain BN

Receptor sequence

>4v6oBN (length=144) Species: 562 (Escherichia coli)

MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGF
EGGQMPLYRRLPKFGFTSRKAAITAEIRLSDLAKVEGGVVDLNTLKAANI
IGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE

3D structure

• PDB: 4v6o Structural characterization of mRNA-tRNA translocation intermediates.
• Chain: BN
• Resolution: 14.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BN	M1 L3 N4 L6 A9 E10 G11 K14 A15 G16 K17 R18 G20 R21 G22 I23 G26 L27 G28 K29 T30 G31 G32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G45 V46 R47 R48 E51 G52 G53 Q54 M55 L57 R59 R60 L61 P62 K63 F64 G65 F66 T67 S68 R69 K70 A71 A72 E76 R78 S80 D81 K84 L95 K96 A98 N99 I100 G102 I103 Q104 K109 I111 L112 R126 T128 K129 G130 E144	M1 L3 N4 L6 A9 E10 G11 K14 A15 G16 K17 R18 G20 R21 G22 I23 G26 L27 G28 K29 T30 G31 G32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G45 V46 R47 R48 E51 G52 G53 Q54 M55 L57 R59 R60 L61 P62 K63 F64 G65 F66 T67 S68 R69 K70 A71 A72 E76 R78 S80 D81 K84 L95 K96 A98 N99 I100 G102 I103 Q104 K109 I111 L112 R126 T128 K129 G130 E144

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v6o, PDBe:4v6o, PDBj:4v6o
• PDBsum: 4v6o
• PubMed: 22467828
• UniProt: P02413|RL15_ECOLI Large ribosomal subunit protein uL15 (Gene Name=rplO)