Structure of PDB 4u24 Chain BN

Receptor sequence

>4u24BN (length=120) Species: 83333 (Escherichia coli K-12) [Search protein sequence]

MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEP
LITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKC
GFRAGDNAPMAYIELVDRSE

3D structure

PDB

4u24 Synergy of streptogramin antibiotics occurs independently of their effects on translation.

Chain

Resolution

2.9 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BN	M1 R2 H3 R4 K5 S6 R8 Q9 N11 R12 N13 S14 H16 R17 A19 M20 R22 N23 M24 S27 H31 I34 K35 T36 T37 P39 K40 K42 R45 R46 E49 P50 T53 V60 R63 R64 F67 A68 R69 R71 N73 A77 R90 A91 G92 G93 R96 K99 R103 G105 D106 N107 A108	M1 R2 H3 R4 K5 S6 R8 Q9 N11 R12 N13 S14 H16 R17 A19 M20 R22 N23 M24 S27 H31 I34 K35 T36 T37 P39 K40 K42 R45 R46 E49 P50 T53 V60 R63 R64 F67 A68 R69 R71 N73 A77 R90 A91 G92 G93 R96 K99 R103 G105 D106 N107 A108

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:4u24, PDBe:4u24, PDBj:4u24
PDBsum	4u24
PubMed	24957822
UniProt	P0AG44\|RL17_ECOLI Large ribosomal subunit protein bL17 (Gene Name=rplQ)