Structure of PDB 8oeq Chain BM

Receptor sequence

>8oeqBM (length=179) Species: 5476 (Candida albicans) [Search protein sequence]

ANLRTQKRLAASVIGVGKRKVWLDPNETTEIANANSRSAIRKLYKNGTIV
KKPETVHSRSRARALKESKRAGRHMGYGKRKGTKDARMPSQVLWMRRLRV
LRKLLAKYRDAGKIDKHLYHNLYKAAKGNTFKHKRSLVEHIIAAKAEALR
EKALKEEAEARRVRNRAARERRQQRLAEK

3D structure

PDB

8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.3 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BM	N3 L4 R5 T6 K8 R9 L10 V17 G18 K19 R20 K21 W23 L24 N36 S37 R38 R42 K43 K46 E55 T56 V57 H58 S59 R60 S61 R62 A63 R64 K70 R71 R74 H75 G77 Y78 G79 K80 R81 K82 G83 T84 K85 R88 M89 Q92 W95 M96 L99 R100 V101 R103 K104 R110 G113 K114 H118 Y120 H121 Y124 K125 K128 G129 N130 H134 K135 K146	N2 L3 R4 T5 K7 R8 L9 V16 G17 K18 R19 K20 W22 L23 N35 S36 R37 R41 K42 K45 E54 T55 V56 H57 S58 R59 S60 R61 A62 R63 K69 R70 R73 H74 G76 Y77 G78 K79 R80 K81 G82 T83 K84 R87 M88 Q91 W94 M95 L98 R99 V100 R102 K103 R109 G112 K113 H117 Y119 H120 Y123 K124 K127 G128 N129 H133 K134 K145
BS02	rna	BM	R162 R163 R165 N166 R170 R172 R173 R176	R161 R162 R164 N165 R169 R171 R172 R175

External links

PDB	RCSB:8oeq, PDBe:8oeq, PDBj:8oeq
PDBsum	8oeq
PubMed
UniProt	A0A1D8PK40\|RL19A_CANAL Large ribosomal subunit protein eL19 (Gene Name=RPL19A)

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