Structure of PDB 4v73 Chain BM

Receptor sequence

>4v73BM (length=136) Species: 83333 (Escherichia coli K-12)

MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTARQIEAAR
RAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGK
VLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM

3D structure

• PDB: 4v73 Energy barriers and driving forces in tRNA translocation through the ribosome.
• Chain: BM
• Resolution: 15.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BM	M1 Q3 K5 R6 R10 P77 V80 R81 N88	M1 Q3 K5 R6 R10 P77 V80 R81 N88
BS02	rna	BM	P4 K5 K8 F9 H13 K14 R16 F28 R44 Q45 A48 R55 K62 W64 F68 D70 K76 L78 M82 K100 K123 L124	P4 K5 K8 F9 H13 K14 R16 F28 R44 Q45 A48 R55 K62 W64 F68 D70 K76 L78 M82 K100 K123 L124
BS03	rna	BM	R18 L20 R38	R18 L20 R38

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v73, PDBe:4v73, PDBj:4v73
• PDBsum: 4v73
• PubMed: 24186064
• UniProt: P0ADY7|RL16_ECOLI Large ribosomal subunit protein uL16 (Gene Name=rplP)