Structure of PDB 4v6p Chain BM

Receptor sequence

>4v6pBM (length=123) Species: 562 (Escherichia coli)

MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRG
KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIF
GPVTRELRSEKFMKIISLAPEVL

3D structure

• PDB: 4v6p Structural characterization of mRNA-tRNA translocation intermediates.
• Chain: BM
• Resolution: 13.5 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BM	R17 E45 I47 P48 R49 K54 R98 M113 I116 S117 L118 P120 L123	R17 E45 I47 P48 R49 K54 R98 M113 I116 S117 L118 P120 L123
BS02	rna	BM	I2 Q3 E4 Q5 T6 M7 R18 M20 I22 K23 L25 G26 G27 S28 H29 R30 R31 Y32 G34 K40 K44 K66 K67 R70 V76 N82	I2 Q3 E4 Q5 T6 M7 R18 M20 I22 K23 L25 G26 G27 S28 H29 R30 R31 Y32 G34 K40 K44 K66 K67 R70 V76 N82

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding
• GO:0070180 large ribosomal subunit rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v6p, PDBe:4v6p, PDBj:4v6p
• PDBsum: 4v6p
• PubMed: 22467828
• UniProt: P0ADY3|RL14_ECOLI Large ribosomal subunit protein uL14 (Gene Name=rplN)