Structure of PDB 4v6o Chain BM

Receptor sequence

>4v6oBM (length=123) Species: 562 (Escherichia coli)

MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRG
KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIF
GPVTRELRSEKFMKIISLAPEVL

3D structure

• PDB: 4v6o Structural characterization of mRNA-tRNA translocation intermediates.
• Chain: BM
• Resolution: 14.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BM	I47 P48 R49 K54 R98 A119 P120 E121 V122 L123	I47 P48 R49 K54 R98 A119 P120 E121 V122 L123
BS02	rna	BM	I2 Q3 E4 Q5 T6 M7 M20 I22 K23 L25 G26 G27 S28 H29 R30 R31 Y32 G34 V35 K40 T42 I43 K44 K66 K67 R70 R71 G74 V76 R78	I2 Q3 E4 Q5 T6 M7 M20 I22 K23 L25 G26 G27 S28 H29 R30 R31 Y32 G34 V35 K40 T42 I43 K44 K66 K67 R70 R71 G74 V76 R78

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding
• GO:0070180 large ribosomal subunit rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v6o, PDBe:4v6o, PDBj:4v6o
• PDBsum: 4v6o
• PubMed: 22467828
• UniProt: P0ADY3|RL14_ECOLI Large ribosomal subunit protein uL14 (Gene Name=rplN)