Structure of PDB 4v6o Chain BL

Receptor sequence

>4v6oBL (length=142) Species: 562 (Escherichia coli)

MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDT
GDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERV
IEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI

3D structure

• PDB: 4v6o Structural characterization of mRNA-tRNA translocation intermediates.
• Chain: BL
• Resolution: 14.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BL	M1 K2 T3 F4 T5 A6 K7 P8 E9 W15 G26 R27 T30 E31 R34 R37 P46 H47 V48 Y53 T65 G66 N67 K68 D71 K72 V73 Y75 T78 G79 H80 I81 G82 G83 I84 Q86 E90 E91 R95 R96 R99 E102 I103 A104 K106 G107 M108 P110 K111 L114 R116 A117 F119 R120 K123 V124 Y125 A126 N131 H132 A134 Q135 Q136	M1 K2 T3 F4 T5 A6 K7 P8 E9 W15 G26 R27 T30 E31 R34 R37 P46 H47 V48 Y53 T65 G66 N67 K68 D71 K72 V73 Y75 T78 G79 H80 I81 G82 G83 I84 Q86 E90 E91 R95 R96 R99 E102 I103 A104 K106 G107 M108 P110 K111 L114 R116 A117 F119 R120 K123 V124 Y125 A126 N131 H132 A134 Q135 Q136

Gene Ontology

Molecular Function

• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0008270 zinc ion binding
• GO:0048027 mRNA 5'-UTR binding
• GO:0070180 large ribosomal subunit rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0017148 negative regulation of translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v6o, PDBe:4v6o, PDBj:4v6o
• PDBsum: 4v6o
• PubMed: 22467828
• UniProt: P0AA10|RL13_ECOLI Large ribosomal subunit protein uL13 (Gene Name=rplM)