Structure of PDB 7zuw Chain BI

Receptor sequence

>7zuwBI (length=218) Species: 4932 (Saccharomyces cerevisiae)

ARRPARCYRYQKNKPYPKSRYNRAVPDSKIRIYDLGKKKATVDEFPLCVH
LVSNELEQLSSEALEAARICANKYMTTVSGRDAFHLRVRVHPFHVLRINK
MLSCAGADRLQQGMRGAWGKPHGLAARVDIGQIIFSVRTKDSNKDVVVEG
LRRARYKFPGQQKIILSKKWGFTNLDRPEYLKKREAGEVKDDGAFVKFLS
KKGSLENNIREFPEYFAA

3D structure

• PDB: 7zuw Structural basis for clearing of ribosome collisions by the RQT complex.
• Chain: BI
• Resolution: 4.3 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BI	Y11 E56 L57 K202 K203 L206 F217	Y10 E55 L56 K201 K202 L205 F216
BS02	rna	BI	R3 R4 P5 A6 R7 C8 K13 N14 K15 Y22 Y34 K40 S61 E63 A64 A67 R88 R90 H92 F94 R98 M102 S104 D109 Q112 Q113 G114 M115 R116 G117 W119 G120 R154 Y157 K158 P160 G194 F196 K198	R2 R3 P4 A5 R6 C7 K12 N13 K14 Y21 Y33 K39 S60 E62 A63 A66 R87 R89 H91 F93 R97 M101 S103 D108 Q111 Q112 G113 M114 R115 G116 W118 G119 R153 Y156 K157 P159 G193 F195 K197
BS03	rna	BI	R110 L111	R109 L110

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0006415 translational termination

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7zuw, PDBe:7zuw, PDBj:7zuw
• PDBsum: 7zuw
• PubMed: 36801861
• UniProt: P41805|RL10_YEAST Large ribosomal subunit protein uL16 (Gene Name=RPL10)