Structure of PDB 7aih Chain BH

Receptor sequence
>7aihBH (length=214) Species: 5664 (Leishmania major) [Search protein sequence]
LYMPYTPVATNPVVYFDITAEGDALGRVSVELFRDVVPRTSENFRSLCTG
ERGYGQCLLYYKGTPFHRIIPGFVMQGGDILTKDGRSNVSVFGYPFPDES
FEGKAGKHLPGTVGMAHSGPNQNGSQFFFNLGRNEQLDRKFVVVGQVLGG
WEIVNQVVKLCGSRCGTPVSRAWISDCGQSGGYMAEETQEALQGERAQHV
IPGKEVLDLIQPRY
3D structure
PDB7aih Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
ChainBH
Resolution3.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R83 F88 Q91 H132 F143 L152 F156
Catalytic site (residue number reindexed from 1) R68 F73 Q76 H117 F128 L137 F141
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna BH Y69 Q71 R101 Q213 V215 Y54 Q56 R86 Q198 V200
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0016018 cyclosporin A binding
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031981 nuclear lumen
GO:0097014 ciliary plasm

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Cellular Component
External links
PDB RCSB:7aih, PDBe:7aih, PDBj:7aih
PDBsum7aih
PubMed33168716
UniProtQ4QBK2

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