Structure of PDB 6tb3 Chain BH

Receptor sequence

>6tb3BH (length=171) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

AHFKEYQVIGRRLPTESVPEPKLFRMRIFASNEVIAKSRYWYFLQKLHKV
KKASGEIVSINQINEAHPTKVKNFGVWVRYDSRSGTHNMYKEIRDVSRVA
AVETLYQDMAARHRARFRSIHILKVAEIEKTADVKRQYVKQFLTKDLKFP
LPHRVQKSTKTFSYKRPSTFY

3D structure

PDB

6tb3 The Ccr4-Not complex monitors the translating ribosome for codon optimality.

Chain

Resolution

2.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BH	A2 N62 N65 H68 K71 S83 R84 S85 M90 Y91 K92 Q108 A111 A112 R113 H114 R115 R117 T132 R137 Y139 L144 T145 K146 H154 R155 Q157 K158 S159 K161 Y165 K166 S169 T170 F171	A1 N61 N64 H67 K70 S82 R83 S84 M89 Y90 K91 Q107 A110 A111 R112 H113 R114 R116 T131 R136 Y138 L143 T144 K145 H153 R154 Q156 K157 S158 K160 Y164 K165 S168 T169 F170
BS02	rna	BH	R13 S39 R40 Y43 Q46 H49 K50 K52 K53 R84 R119	R12 S38 R39 Y42 Q45 H48 K49 K51 K52 R83 R118

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6tb3, PDBe:6tb3, PDBj:6tb3
PDBsum	6tb3
PubMed	32299921
UniProt	P0CX23\|RL20A_YEAST Large ribosomal subunit protein eL20A (Gene Name=RPL20A)

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