Structure of PDB 4v6r Chain BH

Receptor sequence

>4v6rBH (length=176) Species: 562 (Escherichia coli) [Search protein sequence]

SRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLT
FGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGN
VINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAY
RRPEPYKGKGVRYADEVVRTKEAKKK

3D structure

PDB

4v6r Structural characterization of mRNA-tRNA translocation intermediates.

Chain

Resolution

11.5 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BH	S1 R2 V3 K5 D38 D59 W61 A62 Q63 G65 T66 A69 L70 V91 G107 F108 S109 H110 K137 Q138 G141 Q142 A145 D146 A149 Y150 R152 P155 Y156 K157 K159 Y163 D165 R169 T170 K171 E172 K174 K175 K176	S1 R2 V3 K5 D38 D59 W61 A62 Q63 G65 T66 A69 L70 V91 G107 F108 S109 H110 K137 Q138 G141 Q142 A145 D146 A149 Y150 R152 P155 Y156 K157 K159 Y163 D165 R169 T170 K171 E172 K174 K175 K176

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding
GO:0070180	large ribosomal subunit rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0046677	response to antibiotic

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Cellular Component

External links

PDB	RCSB:4v6r, PDBe:4v6r, PDBj:4v6r
PDBsum	4v6r
PubMed	22467828
UniProt	P0AG55\|RL6_ECOLI Large ribosomal subunit protein uL6 (Gene Name=rplF)

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