Structure of PDB 4v6l Chain BH

Receptor sequence

>4v6lBH (length=176) Species: 83333 (Escherichia coli K-12) [Search protein sequence]

SRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLT
FGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGN
VINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAY
RRPEPYKGKGVRYADEVVRTKEAKKK

3D structure

PDB

4v6l Structural insights into cognate versus near-cognate discrimination during decoding.

Chain

Resolution

13.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BH	S1 R2 A4 K5 L36 W61 A62 Q63 G65 T66 R68 A69 L70 K85 G107 F108 S109 H110 P111 K137 Q138 G141 Q142 A145 E154 P155 Y156 K157 K159 Y163 K171 A173 K174 K175 K176	S1 R2 A4 K5 L36 W61 A62 Q63 G65 T66 R68 A69 L70 K85 G107 F108 S109 H110 P111 K137 Q138 G141 Q142 A145 E154 P155 Y156 K157 K159 Y163 K171 A173 K174 K175 K176

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding
GO:0070180	large ribosomal subunit rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0046677	response to antibiotic

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:4v6l, PDBe:4v6l, PDBj:4v6l
PDBsum	4v6l
PubMed	21378755
UniProt	P0AG55\|RL6_ECOLI Large ribosomal subunit protein uL6 (Gene Name=rplF)

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