Structure of PDB 4v6p Chain BG

Receptor sequence

>4v6pBG (length=178) Species: 562 (Escherichia coli)

AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLD
NAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFE
RLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRG
LDITITTTAKSDEEGRALLAAFDFPFRK

3D structure

• PDB: 4v6p Structural characterization of mRNA-tRNA translocation intermediates.
• Chain: BG
• Resolution: 13.5 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BG	A1 H4 D5 K8 S23 V24 M25 R29 E31 K32 Q62 R70 K87 T89 R91 E93 W96 R124 T158	A1 H4 D5 K8 S23 V24 M25 R29 E31 K32 Q62 R70 K87 T89 R91 E93 W96 R124 T158
BS02	rna	BG	T34 N36 M37 G38 V39 G40 E41 K68 A69 R70 K71 V73 F76 Q80 I84 R114 S120 D122 R124 N126 Y127 S128 G130 R132 R149 G150 L151 D152 T156	T34 N36 M37 G38 V39 G40 E41 K68 A69 R70 K71 V73 F76 Q80 I84 R114 S120 D122 R124 N126 Y127 S128 G130 R132 R149 G150 L151 D152 T156

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v6p, PDBe:4v6p, PDBj:4v6p
• PDBsum: 4v6p
• PubMed: 22467828
• UniProt: P62399|RL5_ECOLI Large ribosomal subunit protein uL5 (Gene Name=rplE)