Structure of PDB 4v6l Chain BG

Receptor sequence

>4v6lBG (length=178) Species: 83333 (Escherichia coli K-12)

AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLD
NAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFE
RLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRG
LDITITTTAKSDEEGRALLAAFDFPFRK

3D structure

• PDB: 4v6l Structural insights into cognate versus near-cognate discrimination during decoding.
• Chain: BG
• Resolution: 13.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BG	K77 R79	K77 R79
BS02	rna	BG	Y21 N22 S23 M25 Q26 E31 K32 Q62 K63 L65 K87 V88 T89 R91 K160 E164	Y21 N22 S23 M25 Q26 E31 K32 Q62 K63 L65 K87 V88 T89 R91 K160 E164
BS03	rna	BG	T34 N36 M37 G38 G40 E41 A42 T67 K68 A69 R70 K71 A74 F76 I78 I84 K87 S120 D122 R124 G125 N126 S128 R132 G150 D152 T154 T156 K178	T34 N36 M37 G38 G40 E41 A42 T67 K68 A69 R70 K71 A74 F76 I78 I84 K87 S120 D122 R124 G125 N126 S128 R132 G150 D152 T154 T156 K178

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v6l, PDBe:4v6l, PDBj:4v6l
• PDBsum: 4v6l
• PubMed: 21378755
• UniProt: P62399|RL5_ECOLI Large ribosomal subunit protein uL5 (Gene Name=rplE)