Structure of PDB 4u24 Chain BG

Receptor sequence
>4u24BG (length=176) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
SRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLT
FGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGN
VINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAY
RRPEPYKGKGVRYADEVVRTKEAKKK
3D structure
PDB4u24 Synergy of streptogramin antibiotics occurs independently of their effects on translation.
ChainBG
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna BG S2 R3 V4 A63 Q64 G66 T67 A70 G108 F109 S110 K138 Q139 G142 Q143 A146 P156 Y157 K158 K160 K172 A174 K175 S1 R2 V3 A62 Q63 G65 T66 A69 G107 F108 S109 K137 Q138 G141 Q142 A145 P155 Y156 K157 K159 K171 A173 K174
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4u24, PDBe:4u24, PDBj:4u24
PDBsum4u24
PubMed24957822
UniProtP0AG55|RL6_ECOLI Large ribosomal subunit protein uL6 (Gene Name=rplF)

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