Structure of PDB 4v97 Chain BF

Receptor sequence

>4v97BF (length=207) Species: 300852 (Thermus thermophilus HB8)

MKEVAVYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTAS
TKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYT
LPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDG
SESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWE
VFQNRIG

3D structure

• PDB: 4v97 Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state.
• Chain: BF
• Resolution: 3.516 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BF	H31 W34 E35 R38 L41 A42 K43 R44 R45 R46 T48 A49 S50 T53 R54 V57 A58 Y59 S60 R62 K63 Q67 K68 H69 G71 R72 A73 R74 H75 G76 I82 V84 V88 V89 F90 P92 R95 Y99 T100 P102 K103 K104 V105 R106 K108 K135 T136 K137 R165 R168 N169 P171 G180 Y184 R205	H31 W34 E35 R38 L41 A42 K43 R44 R45 R46 T48 A49 S50 T53 R54 V57 A58 Y59 S60 R62 K63 Q67 K68 H69 G71 R72 A73 R74 H75 G76 I82 V84 V88 V89 F90 P92 R95 Y99 T100 P102 K103 K104 V105 R106 K108 K135 T136 K137 R165 R168 N169 P171 G180 Y184 R205
BS02	MG	BF	R168 L170 V173	R168 L170 V173

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v97, PDBe:4v97, PDBj:4v97
• PDBsum: 4v97
• PubMed: 23630274
• UniProt: Q5SHN9|RL4_THET8 Large ribosomal subunit protein uL4 (Gene Name=rplD)