Structure of PDB 4v6o Chain BE

Receptor sequence

>4v6oBE (length=209) Species: 562 (Escherichia coli) [Search protein sequence]

MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQV
TTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVEL
FADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQ
TPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSD
LIVKPAVKA

3D structure

PDB

4v6o Structural characterization of mRNA-tRNA translocation intermediates.

Chain

Resolution

14.7 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BE	V9 M11 R13 P23 K38 N42 D43 Y45 K55 K56 N58 R59 T61 K62 P63 E64 H67 K70 L79 E81 R83 D108 S113 K114 G115 K116 G117 F118 V122 K123 R124 N126 R128 T129 Q130 D131 T133 H134 G135 N136 S137 L138 S139 H140 R141 P143 G144 S145 I146 G147 Q148 N149 Q150 T151 P152 G153 K154 V155 F156 K159 M161 A162 G163 Q164 M165 G166 N167 R169 T171 V172 Q173 S174 L175 K190 G191 A192 V193 P194 G195 A196 T197 G198 S199 V207 A209	V9 M11 R13 P23 K38 N42 D43 Y45 K55 K56 N58 R59 T61 K62 P63 E64 H67 K70 L79 E81 R83 D108 S113 K114 G115 K116 G117 F118 V122 K123 R124 N126 R128 T129 Q130 D131 T133 H134 G135 N136 S137 L138 S139 H140 R141 P143 G144 S145 I146 G147 Q148 N149 Q150 T151 P152 G153 K154 V155 F156 K159 M161 A162 G163 Q164 M165 G166 N167 R169 T171 V172 Q173 S174 L175 K190 G191 A192 V193 P194 G195 A196 T197 G198 S199 V207 A209

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:4v6o, PDBe:4v6o, PDBj:4v6o
PDBsum	4v6o
PubMed	22467828
UniProt	P60438\|RL3_ECOLI Large ribosomal subunit protein uL3 (Gene Name=rplC)

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