Structure of PDB 4v4z Chain BE

Receptor sequence

>4v4zBE (length=206) Species: 300852 (Thermus thermophilus HB8)

MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLG
FLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGE
RVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRV
YKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRE
TKKAAK

3D structure

• PDB: 4v4z Structural basis for messenger RNA movement on the ribosome.
• Chain: BE
• Resolution: 4.51 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BE	M11 T12 R19 V21 R36 E40 K41 G43 K57 V59 N60 R61 K64 G65 I77 L78 R79 I81 K109 G110 R111 G112 F113 G115 M117 W120 N121 F122 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 P138 G139 S140 I141 G142 N143 R144 K145 T146 G148 R149 V150 Y151 K152 G153 K154 M156 H159 A162 R164 V165 T166 M168 N169 K185 A187 G190 P191 N192 K203 A204 A205 K206	M11 T12 R19 V21 R36 E40 K41 G43 K57 V59 N60 R61 K64 G65 I77 L78 R79 I81 K109 G110 R111 G112 F113 G115 M117 W120 N121 F122 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 P138 G139 S140 I141 G142 N143 R144 K145 T146 G148 R149 V150 Y151 K152 G153 K154 M156 H159 A162 R164 V165 T166 M168 N169 K185 A187 G190 P191 N192 K203 A204 A205 K206

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v4z, PDBe:4v4z, PDBj:4v4z
• PDBsum: 4v4z
• PubMed: 17051149
• UniProt: Q5SHN8|RL3_THET8 Large ribosomal subunit protein uL3 (Gene Name=rplC)