Structure of PDB 9f1c Chain BC

Receptor sequence

>9f1cBC (length=362) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

ACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQP
YAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRM
FAPTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVPELP
LVVEDKVEGYKKTKEAVLLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRR
IQRRGPCVIYNEDNGIVKAFRNIPGITLLNVTKLNILKLAPGGHVGRFCI
WTESAFRKLDDLYGTWRKAASLKSNYNLPMHKMLNTDLSRILKSPEIQRA
LRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRV
ERAAAALAAKSD

3D structure

PDB

9f1c NAC guides a ribosomal multienzyme complex for nascent protein processing.

Chain

Resolution

3.78 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BC	P51 A53 V54 S55 M196	P50 A52 V53 S54 M195
BS02	rna	BC	A2 C3 A4 R5 P6 K29 R33 I36 F39 T42 N43 R45 K46 N48 R49 Q50 Y52 S55 E56 A58 G59 H60 Q61 T62 S63 T69 G70 A72 V73 A74 R75 P77 V79 R80 G83 T84 R86 Q89 N94 M95 R97 G98 R100 M101 F102 A103 P104 K106 W108 R109 R110 R113 R114 N116 T117 T118 Q119 K120 R121 Y122 K140 R143 K163 T164 K165 K172 K182 Y184 R188 R190 A191 G192 K195 R197 R199 R201 R204 R205 K219 R222 N223 N236 P242 G243 H245 W267 R268 K269 K274 S275 M281 H282 R291 L293 K294 R303 A304 P305 R306 K307 K308 H310 R311 R312 V313 K316 K320 N321 L322 R323 K333 M335 T339 R342 Q343 N346 H347 R350 R353	A1 C2 A3 R4 P5 K28 R32 I35 F38 T41 N42 R44 K45 N47 R48 Q49 Y51 S54 E55 A57 G58 H59 Q60 T61 S62 T68 G69 A71 V72 A73 R74 P76 V78 R79 G82 T83 R85 Q88 N93 M94 R96 G97 R99 M100 F101 A102 P103 K105 W107 R108 R109 R112 R113 N115 T116 T117 Q118 K119 R120 Y121 K139 R142 K162 T163 K164 K171 K181 Y183 R187 R189 A190 G191 K194 R196 R198 R200 R203 R204 K218 R221 N222 N235 P241 G242 H244 W266 R267 K268 K273 S274 M280 H281 R290 L292 K293 R302 A303 P304 R305 K306 K307 H309 R310 R311 V312 K315 K319 N320 L321 R322 K332 M334 T338 R341 Q342 N345 H346 R349 R352

External links

PDB	RCSB:9f1c, PDBe:9f1c, PDBj:9f1c
PDBsum	9f1c
PubMed	39169182
UniProt	G1SVW5\|RL4_RABIT Large ribosomal subunit protein uL4 (Gene Name=RPL4)

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