Structure of PDB 8s1r Chain BBB

Receptor sequence
>8s1rBBB (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGSDYIIKEKTVLLQKKDSEGFGFVLRGAKEFTPTPAFPALQYLESVD
EGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMV
TRHP
3D structure
PDB8s1r Biophysical and structural analyses of the interaction between the SHANK1 PDZ domain and an internal SLiM.
ChainBBB
Resolution1.979 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide BBB D670 E672 G673 G675 F676 V677 L678 R679 G680 K682 Y701 E703 D706 H735 R736 V739 D20 E22 G23 G25 F26 V27 L28 R29 G30 K32 Y45 E47 D50 H79 R80 V83
External links
PDB RCSB:8s1r, PDBe:8s1r, PDBj:8s1r
PDBsum8s1r
PubMed38899489
UniProtQ9Y566|SHAN1_HUMAN SH3 and multiple ankyrin repeat domains protein 1 (Gene Name=SHANK1)

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