Structure of PDB 8ohr Chain BBB

Receptor sequence
>8ohrBBB (length=74) Species: 9606 (Homo sapiens) [Search protein sequence]
QDVVDLDFFTQEPLHLVSPSFLSVTIDANLATDPRFLILLGSPKLRTLAR
GLSPAYLRFGGTKTDFLIFDPKKE
3D structure
PDB8ohr Molecular Basis for Inhibition of Heparanases and beta-Glucuronidases by Siastatin B.
ChainBBB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.166: heparanase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 VP5 BBB D27 G61 T62 D27 G61 T62
External links
PDB RCSB:8ohr, PDBe:8ohr, PDBj:8ohr
PDBsum8ohr
PubMed38118176
UniProtQ9Y251|HPSE_HUMAN Heparanase (Gene Name=HPSE)

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