Structure of PDB 8ohq Chain BBB

Receptor sequence
>8ohqBBB (length=74) Species: 9606 (Homo sapiens) [Search protein sequence]
QDVVDLDFFTQEPLHLVSPSFLSVTIDANLATDPRFLILLGSPKLRTLAR
GLSPAYLRFGGTKTDFLIFDPKKE
3D structure
PDB8ohq Molecular Basis for Inhibition of Heparanases and beta-Glucuronidases by Siastatin B.
ChainBBB
Resolution1.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.2.1.166: heparanase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 VGO BBB D27 G61 T62 D27 G61 T62
External links
PDB RCSB:8ohq, PDBe:8ohq, PDBj:8ohq
PDBsum8ohq
PubMed38118176
UniProtQ9Y251|HPSE_HUMAN Heparanase (Gene Name=HPSE)

[Back to BioLiP]