Structure of PDB 8bp2 Chain BBB

Receptor sequence
>8bp2BBB (length=189) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEK
ARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHI
RTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEH
RALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVY
3D structure
PDB8bp2 A 2.8 angstrom Structure of Zoliflodacin in a DNA Cleavage Complex with Staphylococcus aureus DNA Gyrase.
ChainBBB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna BBB E435 K460 D512 E19 K44 D96
BS02 dna BBB D437 S438 D21 S22
BS03 dna BBB L462 N463 K466 H515 V626 R629 L46 N47 K50 H99 V176 R179
BS04 MN BBB D508 D510 D92 D94
BS05 R8U BBB G436 R458 G459 G20 R42 G43
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:8bp2, PDBe:8bp2, PDBj:8bp2
PDBsum8bp2
PubMed36675148
UniProtP66937|GYRB_STAAN DNA gyrase subunit B (Gene Name=gyrB)

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