Structure of PDB 7qe3 Chain BBB

Receptor sequence
>7qe3BBB (length=322) Species: 946362 (Salpingoeca rosetta) [Search protein sequence]
FEPATDSPLPVPGVQYFLQHVQSGKYVHPHGGSDMPGNDTALVLHHGFDE
KRDALRWVFVNDAENKHQLKHYSSGKFVHPKGGKVGKEATLVVHSSPGRP
ETMIEMVQEDGRTYLRHTDSDYYVHPHGGSPNPGDNTRLVYYSGYRPSLA
FLAIPAETLFVDRIEIHQAQALESINTITSLSDEHRNDTDPVQTSISVAL
EESLQDSAQLSFERCFGLKVGSEFEVGLPLVGKTKVSVQFSGSWKSSTIK
GEVRTSAVKVQINEHVTIPPGKCVQIRIDTRRCTKTAPATMYLRTASGIE
VQRETTVTSTYHYDQEVHVVPV
3D structure
PDB7qe3 The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3.
ChainBBB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 1JW BBB H34 G35 H49 R56 N140 H30 G31 H45 R52 N136
BS02 1JW BBB D43 H83 K85 S100 R103 D39 H79 K81 S96 R99
BS03 1JW BBB E92 H129 H131 G132 Y146 R150 E88 H125 H127 G128 Y142 R146
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