Structure of PDB 7ou8 Chain BBB

Receptor sequence
>7ou8BBB (length=708) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search protein sequence]
VSLQPPPQQLIVQNKTIDLPAVYQLNGGEEANPHAVKVLKELLSGKQSSK
KGMLISIGEKGDKSVRKYSRQIPDHKEGYYLSVNEKEIVLAGNDERGTYY
ALQTFAQLLKDGKLPEVEIKDYPSVRYRGVVEGFYGTPWSHQARLSQLKF
YGKNKMNTYIYGPKDDPYHSAPNWRLPYPDKEAAQLQELVAVANENEVDF
VWAIHPGQDIKWNKEDRDLLLAKFEKMYQLGVRSFAVFFDDISGEGTNPQ
KQAELLNYIDEKFAQVKPDINQLVMCPTEYNKSWSNPNGNYLTTLGDKLN
PSIQIMWTGDRVISDITRDGISWINERIKRPAYIWWNFPVSDYVRDHLLL
GPVYGNDTTIAKEMSGFVTNPMEHAESSKIAIYSVASYAWNPAKYDTWQT
WKDAIRTILPSAAEELECFAMHNSDLGPNGHGYRREESMDIQPAAERFLK
AFKEGKNYDKADFETLQYTFERMKESADILLMNTENKPLIVEITPWVHQF
KLTAEMGEEVLKMVEGRNESYFLRKYNHVKALQQQMFYIDQTSNQNPYQP
GVKTATRVIKPLIDRTFATVVKFFNQKFNAHLDATTDYMPHKMISNVEQI
KNLPLQVKANRVLISPANEVVKWAAGNSVEIELDAIYPGENIQINFGKDA
TWGRLEISTDGKEWKTVDLKQKESRLSAGLQKAPVKFVRFTNVSDEEQLR
QFVLTIEK
3D structure
PDB7ou8 Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications
ChainBBB
Resolution1.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.2.1.169: protein O-GlcNAcase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 1XI BBB G135 K166 D242 D243 Y282 V314 W337 N339 D344 G133 K164 D240 D241 Y280 V312 W335 N337 D342
BS02 CA BBB E32 E61 D64 E30 E59 D62
External links
PDB RCSB:7ou8, PDBe:7ou8, PDBj:7ou8
PDBsum7ou8
PubMed
UniProtQ89ZI2|OGA_BACTN O-GlcNAcase BT_4395 (Gene Name=BT_4395)

[Back to BioLiP]