Structure of PDB 7oiq Chain BBB

Receptor sequence
>7oiqBBB (length=250) Species: 10116 (Rattus norvegicus) [Search protein sequence]
HQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYL
SGMPECKFGMNDKISIAIDDCTFHQCVRLSERSISFIPPDGEFELMRYRT
TKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLN
TSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPWARPP
ISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC
3D structure
PDB7oiq FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
ChainBBB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide BBB F174 K420 W421 V422 R423 F18 K235 W236 V237 R238
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7oiq, PDBe:7oiq, PDBj:7oiq
PDBsum7oiq
PubMed35486718
UniProtP84092|AP2M1_RAT AP-2 complex subunit mu (Gene Name=Ap2m1)

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