Structure of PDB 7nw1 Chain BBB

Receptor sequence
>7nw1BBB (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
DEATRRVVSEIPVLKTNAGPRDRELWVQRLKEEYQSLIRYVENNKNADND
WFRLESNKEGTRWFGKCWYIHDLLKYEFDIEFDIPITYPTTAPEIAVPEL
DGKTAKMYRGGKICLTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEIPD
LIQKGVIQHKEKC
3D structure
PDB7nw1 Structural basis for UFM1 transfer from UBA5 to UFC1.
ChainBBB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide BBB K33 Y36 I40 V43 K47 R55 K31 Y34 I38 V41 K45 R53
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0061657 UFM1 conjugating enzyme activity
GO:0071568 UFM1 transferase activity
Biological Process
GO:0007420 brain development
GO:0032649 regulation of type II interferon production
GO:0034976 response to endoplasmic reticulum stress
GO:0061709 reticulophagy
GO:0071569 protein ufmylation
GO:1990592 protein K69-linked ufmylation
Cellular Component
GO:0070062 extracellular exosome

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External links
PDB RCSB:7nw1, PDBe:7nw1, PDBj:7nw1
PDBsum7nw1
PubMed34588452
UniProtQ9Y3C8|UFC1_HUMAN Ubiquitin-fold modifier-conjugating enzyme 1 (Gene Name=UFC1)

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