Structure of PDB 6z6c Chain BBB

Receptor sequence
>6z6cBBB (length=317) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
GHMSTPGAQQVLFRTGIAAVNSTNHLRVYFQDVYGSIRESLYEGSWANGT
EKNVIGNAKLGSPVAATSKELKHIRVYTLTEGNTLQEFAYDSGTGWYNGG
LGGAKFQVAPYSCIAAVFLAGTDALQLRIYAQKPDNTIQEYMWNGDGWKE
GTNLGGALPGTGIGATSFRYTDYNGPSIRIWFQTDDLKLVQRAYDPHKGW
YPDLVTIFDRAPPRTAIAATSFGAGNSSIYMRIYFVNSDNTIWQVCWDHG
KGYHDKGTITPVIQGSEVAIISWGSFANNGPDLRLYFQNGTYISAVSEWV
WNRAHGSQLGRSALPPA
3D structure
PDB6z6c Hexavalent thiofucosides to probe the role of the Aspergillus fumigatus lectin FleA in fungal pathogenicity.
ChainBBB
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Q9Q BBB R25 E37 E41 Y88 R27 E39 E43 Y90
BS02 Q9Q BBB R73 E85 G97 G98 L123 W141 W146 R75 E87 G99 G100 L125 W143 W148
BS03 Q9Q BBB R126 E138 M140 N142 T150 I176 Y192 W198 R128 E140 M142 N144 T152 I178 Y194 W200
BS04 Q9Q BBB R230 Q242 D253 W299 R232 Q244 D255 W301
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process

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Molecular Function
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Biological Process
External links
PDB RCSB:6z6c, PDBe:6z6c, PDBj:6z6c
PDBsum6z6c
PubMed33885578
UniProtQ4WW81|LECF_ASPFU Fucose-specific lectin (Gene Name=fleA)

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