Structure of PDB 6yq3 Chain BBB

Receptor sequence

>6yq3BBB (length=254) Species: 2093747 (Streptomyces sp. QL37) [Search protein sequence]

SRLTGKNALVTGSSRGIGRATAVRLAREGALVAVHYASNEAAADETVAQI
EREGGRAFPVRAELGVAGDVHELFLGLEQGLKERTGETTLDILVNNAAVT
GVDGILPEDVTAEQLDRYYAVNAKAPFLLVQRAVRNMPDGGRIINISSGL
TRCAVPEQVAYSMTKGALEQITLHMAKHLAPRGITVNSVAPGITDNGGAV
FDIPEIVEQMAQSSAFKRVGEAGDVADVVTFIATDESRWITGAFIDASGG
TLLG

3D structure

PDB

6yq3 Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway.

Chain

BBB

Resolution

1.57 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	G17 S149 Y162
Catalytic site (residue number reindexed from 1)	G16 S148 Y161
Enzyme Commision number	?

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAP	BBB	G13 S15 R16 G17 I18 H36 A38 S39 N40 L65 N97 A98 A99 V122 I147 S148 S149 Y162 K166 P192 G193 I194 T195 N197	G12 S14 R15 G16 I17 H35 A37 S38 N39 L64 N96 A97 A98 V121 I146 S147 S148 Y161 K165 P191 G192 I193 T194 N196
BS02	P7Q	BBB	T101 G102 V103 S149 G150 L151 Q159 Y162 G193 I194 T252	T100 G101 V102 S148 G149 L150 Q158 Y161 G192 I193 T251

Gene Ontology

	Molecular Function
GO:0016491	oxidoreductase activity

View graph for
Molecular Function

External links

PDB	RCSB:6yq3, PDBe:6yq3, PDBj:6yq3
PDBsum	6yq3
PubMed	32840360
UniProt	A0A2S6PN47

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