Structure of PDB 6yjv Chain BBB

Receptor sequence
>6yjvBBB (length=502) Species: 9606 (Homo sapiens) [Search protein sequence]
SLAEIRTDFNILYSMMKKHEEFRWMRLRIRRMADAWIQAIKSLAEKQNLE
KRKRKKVLVHLGLLTKESGFKIAETAFSGGPLGELVQWSDLITSLYLLGH
DIRISASLAELKEIMGGGGVELIYIDIVGLAQFKKTLGPSWVHYQCMLRV
LDSFGTEPEFNHANYAQSKGHKTPWGKWNLNPQQFYTMFPHTPDNSFLGF
VVEQHLNNEIKRQNQSLVYGKVDSFWKNKKIYLDIIHTYMEVHATVYTKN
IPSYVKNHGILSGRDLQFLLRETKLFVGLGFPYEGPAPLEAIANGCAFLN
PKFNPPKSSKNTDFFIGKPTLRELTSQHPYAEVFIGRPHVWTVDLNNQEE
VEDAVKAILNQKIEPYMPYEFTCEGMLQRINAFIEKQDFCHMWPPLSALQ
VKLAEPGQSCKQVCQESQLICEPSFFQHLNKDKDMLKYKVTCQSSELAKD
ILVPSFDPKNKHCVFQGDLLLFSCAGAHPRHQRVCPCRDFIKGQVALCKD
CL
3D structure
PDB6yjv Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
ChainBBB
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.155: alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN BBB P294 E297 F537 K541 P81 E84 F314 K318
BS02 U2F BBB P294 L295 G296 S366 F367 Y439 K441 I483 L484 L489 F504 P505 Y506 G508 P509 A510 E513 F537 P81 L82 G83 S153 F154 Y219 K221 I260 L261 L266 F281 P282 Y283 G285 P286 A287 E290 F314
Gene Ontology
Molecular Function
GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
Biological Process
GO:0006487 protein N-linked glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6yjv, PDBe:6yjv, PDBj:6yjv
PDBsum6yjv
PubMed
UniProtQ09328|MGT5A_HUMAN Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Gene Name=MGAT5)

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