Structure of PDB 6yju Chain BBB

Receptor sequence
>6yjuBBB (length=501) Species: 9606 (Homo sapiens) [Search protein sequence]
SLAEIRTDFNILYSMMKKHEEFRWMRLRIRRMADAWIQAIKSLAEKQNLE
KRKRKKVLVHLGLLTKESGFKIAETAFSGGPLGELVQWSDLITSLYLLGH
DIRISASLAELKEIMGGGGVELIYIDIVGLAQFKKTLGPSWVHYQCMLRV
LDSFGTEPEFNHANYAQSKGHKTPWGKWNLNPQQFYTMFPHTPDNSFLGF
VVEQHLNEIKRQNQSLVYGKVDSFWKNKKIYLDIIHTYMEVHATVYTKNI
PSYVKNHGILSGRDLQFLLRETKLFVGLGFPYEGPAPLEAIANGCAFLNP
KFNPPKSSKNTDFFIGKPTLRELTSQHPYAEVFIGRPHVWTVDLNNQEEV
EDAVKAILNQKIEPYMPYEFTCEGMLQRINAFIEKQDFCHMWPPLSALQV
KLAEPGQSCKQVCQESQLICEPSFFQHLNKDKDMLKYKVTCQSSELAKDI
LVPSFDPKNKHCVFQGDLLLFSCAGAHPRHQRVCPCRDFIKGQVALCKDC
L
3D structure
PDB6yju Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
ChainBBB
Resolution1.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.155: alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN BBB P294 E297 F537 K541 P81 E84 F313 K317
BS02 UDP BBB L295 G296 Y439 K441 I483 L484 L489 G508 P509 A510 E513 L82 G83 Y218 K220 I259 L260 L265 G284 P285 A286 E289
Gene Ontology
Molecular Function
GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
Biological Process
GO:0006487 protein N-linked glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6yju, PDBe:6yju, PDBj:6yju
PDBsum6yju
PubMed
UniProtQ09328|MGT5A_HUMAN Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Gene Name=MGAT5)

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