Structure of PDB 6yjt Chain BBB

Receptor sequence
>6yjtBBB (length=506) Species: 9606 (Homo sapiens) [Search protein sequence]
SLAEIRTDFNILYSMMKKHEEFRWMRLRIRRMADAWIQAIKSLAEKQNLE
KRKRKKVLVHLGLLTKESGFKIAGGPLGELVQWSDLITSLYLLGHDIRIS
ASLAELKEIMGGGGVELIYIDIVGLAQFKKTLGPSWVHYQCMLRVLDSFG
TEPEFNHANYAQSKGHKTPWGKWNLNPQQFYTMFPHTPDNSFLGFVVEQH
LNSSDIHHINEIKRQNQSLVYGKVDSFWKNKKIYLDIIHTYMEVHATVYG
TKNIPSYVKNHGILSGRDLQFLLRETKLFVGLGFPYEGPAPLEAIANGCA
FLNPKFNPPKSSKNTDFFIGKPTLRELTSQHPYAEVFIGRPHVWTVDLNN
QEEVEDAVKAILNQKIEPYMPYEFTCEGMLQRINAFIEKQDFCHGMWPPL
SALQVKLAEPGQSCKQVCQESQLICEPSFFQHLNKDKDMLKYKVTCQSSE
LAKDILVPSFDPKNKHCVFQGDLLLFSCAGAHPRHQRVCPCRDFIKGQVA
LCKDCL
3D structure
PDB6yjt Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
ChainBBB
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.155: alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UDP BBB P294 L295 G296 Y439 K441 T465 I483 L484 L489 G508 P509 A510 E513 P76 L77 G78 Y221 K223 T247 I263 L264 L269 G288 P289 A290 E293
Gene Ontology
Molecular Function
GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
Biological Process
GO:0006487 protein N-linked glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6yjt, PDBe:6yjt, PDBj:6yjt
PDBsum6yjt
PubMed
UniProtQ09328|MGT5A_HUMAN Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Gene Name=MGAT5)

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