Structure of PDB 6vvh Chain BBB

Receptor sequence
>6vvhBBB (length=313) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
EDKNRTNTDDIRSLRVITAIKTPYLPDGRFDLQAYDDLVNTQIENGAEGV
IVGGTTGEGQLMSWDEHIMLIGHTVNCFGGRIKVIGNTGSNSTREAIHAT
EQGFAMGMHGALHINPYYGKTSIEGMNAHFQTVLHMGPTIIYNVPGRTCQ
DIPPQVIFKLSQNPNMAGVKECVGNNRVEEYTEKGIVVWSGNDDQCHDSR
WDHGATGVISVTSNLVPGLMRKLMFEGRNSALNAKLLPLMDWLFQEPNPI
GVNTALAQLGVARPVFRLPYVPLPLSKRIEFVKLVKEIGREHFVGDRDVQ
VLDDDDFILIGRY
3D structure
PDB6vvh Differential lysine-mediated allosteric regulation of plant dihydrodipicolinate synthase isoforms.
ChainBBB
Resolution1.792 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T107 Y170 Y194 R199 K222 I261
Catalytic site (residue number reindexed from 1) T55 Y118 Y142 R147 K170 I209
Enzyme Commision number 4.3.3.7: 4-hydroxy-tetrahydrodipicolinate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LYS BBB N143 E147 N91 E95
BS02 LYS BBB G111 Q112 M114 W116 H119 Y169 G59 Q60 M62 W64 H67 Y117
Gene Ontology
Molecular Function
GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase activity
GO:0016829 lyase activity
Biological Process
GO:0009089 lysine biosynthetic process via diaminopimelate

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Molecular Function
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Biological Process
External links
PDB RCSB:6vvh, PDBe:6vvh, PDBj:6vvh
PDBsum6vvh
PubMed33586321
UniProtQ9LZX6|DAPA1_ARATH 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic (Gene Name=DHDPS1)

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