Structure of PDB 9f1c Chain BA

Receptor sequence

>9f1cBA (length=253) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHD
PGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNV
LPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLP
SGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRG
VAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKT
VQE

3D structure

PDB

9f1c NAC guides a ribosomal multienzyme complex for nascent protein processing.

Chain

Resolution

3.78 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BA	G2 R3 V4 Q8 R9 K10 G11 S14 R17 A18 H19 V20 K21 H22 R23 K24 G25 A26 F34 R37 G39 Y40 I44 H50 P52 R54 R64 Y67 R68 F69 R72 G85 Y89 A94 Q95 E118 G121 K125 L126 A127 R128 A129 S130 G131 N132 L150 P151 S152 K156 R174 I175 K177 L180 A182 G183 Y186 H187 K188 K190 R193 N194 W196 P197 R198 V199 R200 G201 V202 A203 M204 N205 V207 E208 G214 N215 X216 Q217 H218 G220 K221 P222 S223 T224 R226 R227 P230 A231 R233 K234 V235 G236 I238 A240 R241 R242 T243 G244 R245 L246	G1 R2 V3 Q7 R8 K9 G10 S13 R16 A17 H18 V19 K20 H21 R22 K23 G24 A25 F33 R36 G38 Y39 I43 H49 P51 R53 R63 Y66 R67 F68 R71 G84 Y88 A93 Q94 E117 G120 K124 L125 A126 R127 A128 S129 G130 N131 L149 P150 S151 K155 R173 I174 K176 L179 A181 G182 Y185 H186 K187 K189 R192 N193 W195 P196 R197 V198 R199 G200 V201 A202 M203 N204 V206 E207 G213 N214 X215 Q216 H217 G219 K220 P221 S222 T223 R225 R226 P229 A230 R232 K233 V234 G235 I237 A239 R240 R241 T242 G243 R244 L245
BS02	rna	BA	R247 G248	R246 G247

External links

PDB	RCSB:9f1c, PDBe:9f1c, PDBj:9f1c
PDBsum	9f1c
PubMed	39169182
UniProt	G1TT27\|RL8_RABIT Large ribosomal subunit protein uL2 (Gene Name=RPL8)

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