Structure of PDB 7qo2 Chain BA

Receptor sequence
>7qo2BA (length=222) Species: 9606 (Homo sapiens) [Search protein sequence]
DLPKSVDWRKKGYVTPVKNQKQCGSAWAFSATGALEGQMFRKTGKLVSLS
EQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICK
YRPENSVAQDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKS
GIYFEPDCSSKNLDHGVLVVGYGFEGANSQNSKYWLVKNSWGPEWGSNGY
VKIAKDKNNHCGIATAASYPNV
3D structure
PDB7qo2 Peptide GAKSAA in complex with human cathepsin V C25A mutant
ChainBA
Resolution1.77 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.43: cathepsin V.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide BA G246 A248 Q286 G290 G291 F292 A359 D386 H387 G24 A26 Q64 G68 G69 F70 A137 D164 H165
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7qo2, PDBe:7qo2, PDBj:7qo2
PDBsum7qo2
PubMed
UniProtO60911|CATL2_HUMAN Cathepsin L2 (Gene Name=CTSV)

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