Structure of PDB 7tns Chain B8

Receptor sequence
>7tnsB8 (length=428) Species: 508771 (Toxoplasma gondii ME49) [Search protein sequence]
MREVISIHVGQAGIQIGNACWELFCLEHGIQPDGQMPDAFNTFFSETGAG
KHVPRCVFLDLEPTVVDEVRTGTYRHLFHPEQLISGKEDAANNFARGHYT
IGKEIVDLSLDRIRKLADNCTGLQGFLMFNAVGGGTGSGLGCLLLERLSV
DYGKKSKLNFCSWPSPQVSTAVVEPYNSVLSTHSLLEHTDVAVMLDNEAI
YDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDVTEFQTNL
VPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPASMMAKCDPRH
GKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQP
PTVVPGGDLAKVMRAVCMISNSTAIAEVFSRMDHKFDLMYAKRAFVHWYV
GEGMEEGEFSEAREDLAALEKDYEEVGI
3D structure
PDB7tns Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures.
ChainB8
Resolution6.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B8 N18 L26 G29 I30 Q31 E77 G81 N18 L26 G29 I30 Q31 E68 G72
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tns, PDBe:7tns, PDBj:7tns
PDBsum7tns
PubMed35121661
UniProtP10873|TBA_TOXGO Tubulin alpha chain

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