Structure of PDB 6lqp Chain B6

Receptor sequence
>6lqpB6 (length=374) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SKTRYYLEQCIPEMDDLVEKGLFTKNEVSLIMKKRTDFEHRLNSRGSSIN
DYIKYINYESNVNKLRAKRCKRILQVKKTNSLSDWSIQQRIGFIYQRGTN
KFPQDLKFWAMYLNYMKARGNQTSYKKIHNIYNQLLKLHPTNVDIWISCA
KYEYEVHANFKSCRNIFQNGLRFNPDVPKLWYEYVKFELNFITKLINRRK
VMGLINALRGDIALTIFDVCMKTLGKHYINKHKGYYAISDSKMNIELNKE
TLNYLFSESLRYIKLFDEFLDLERDYLINHVLQFWKNDMYDLSLRKDLPE
LYLKTVMIDITLNIRYMPVEKLDIDQLQLSVKKYFAYISKLDSASVKSLK
NEYRSYLQDNAEDDPRYKILDLII
3D structure
PDB6lqp Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
ChainB6
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna B6 K3 Y6 Y7 R46 K78 K79 N81 L83 W86 Q90 F94 Q97 K102 R120 N122 Q123 K162 K2 Y5 Y6 R45 K77 K78 N80 L82 W85 Q89 F93 Q96 K101 R119 N121 Q122 K161
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030515 snoRNA binding
GO:0034511 U3 snoRNA binding
GO:0042802 identical protein binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6lqp, PDBe:6lqp, PDBj:6lqp
PDBsum6lqp
PubMed32943522
UniProtQ02354|UTP6_YEAST U3 small nucleolar RNA-associated protein 6 (Gene Name=UTP6)

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