Structure of PDB 4u20 Chain B5

Receptor sequence
>4u20B5 (length=190) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
KVYTIDEAARTAKFDETVEVHAKLGIDPRRSDQNVRGTVSLPHGLGKQVR
VLAIAKGEKIKEAEEAGADYVGGEEIIQKILDGWMDFVMGAVGSKLGRIL
GPRGLNPKAGTVGFNIGEIIREIKAGRIEFRNDKTGAIHAPVGKASFPPE
KLADNIRAFIRALEAHKPEGAKGTFLRSVYVTTTMGPSVR
3D structure
PDB4u20 Synergy of streptogramin antibiotics occurs independently of their effects on translation.
ChainB5
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B5 T35 A36 K37 T41 E43 H45 K47 M109 L137 N140 T169 G170 V176 G177 V215 M219 T11 A12 K13 T17 E19 H21 K23 M85 L105 N106 T135 G136 V142 G143 V181 M185
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0006417 regulation of translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4u20, PDBe:4u20, PDBj:4u20
PDBsum4u20
PubMed24957822
UniProtQ5SLP7|RL1_THET8 Large ribosomal subunit protein uL1 (Gene Name=rplA)

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