Structure of PDB 4woi Chain B3

Receptor sequence

>4woiB3 (length=64) Species: 83333 (Escherichia coli K-12)

PKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVS
KGDLGLVIACLPYA

3D structure

• PDB: 4woi Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions.
• Chain: B3
• Resolution: 3.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	B3	P1 K2 I3 K4 T5 R7 K11 R12 T16 K18 K22 H25 A26 N27 R29 H30 I31 L32 T33 K34 T37 K38 R39 K40 R41 H42 R44 M48 S50 K51 D53 L56 Y63	P1 K2 I3 K4 T5 R7 K11 R12 T16 K18 K22 H25 A26 N27 R29 H30 I31 L32 T33 K34 T37 K38 R39 K40 R41 H42 R44 M48 S50 K51 D53 L56 Y63

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4woi, PDBe:4woi, PDBj:4woi
• PDBsum: 4woi
• PubMed: 26224058
• UniProt: P0A7Q1|RL35_ECOLI Large ribosomal subunit protein bL35 (Gene Name=rpmI)